A few thoughts on the major awards:
The best supporting awards are locks -- Mo'Nique and Christopher Waltz. Both deserving.
Best Actor will go to Jeff Bridges in a walk.
Best Actress is really up in the air. They could give it to Meryl -- she's been nominated a zillion times, but hasn't won in 28 years, and was great as Julia Child. They could give it to Sandra Bullock, though it feels like just being nominated is the prize for her. They could easily give it to Carey Mulligan or Gabourey Sidibe, but both are young, and it's unclear if they were just acting or being themselves. My pick is Meryl, though it might be Sandy.
Best Director will be Kathryn Bigelow, because it's time, and it's a great movie.
Best Picture could go either way, to Avatar or Hurt Locker, with Inglourious Basterds having a tiny shot at sneaking in. The last time a movie won for Best Picture without being nominated for Best Screenplay was Titanic... But I'm going to say Hurt Locker.
Best Song will be the Crazy Heart song, and hopefully the interpretive dance number won't be horrible.
Best Adapted Screenplay goes to Up In The Air, easily.
Best Original Screenplay is between Hurt Locker and Inglourious Basterds. Could go either way, though I read Hurt Locker (after seeing the movie ) and was impressed about how much was on the page. Let's pick Hurt Locker in a Harvey backlash.
Everything else, you're on your own, Oscar pool wise. Though I hear Wallace and Gromit may win another.